Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344152 | 0.83 | MEN1 (0.38) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11631287 | 0.82 | MEN1 (0.34) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9340255 | 0.82 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11631333 | 0.81 | MEN1 (0.34) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11632480 | 0.80 | POLB (0.41) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11633266 | 0.79 | NPC1 (0.37) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7698979 | 0.78 | MEN1 (0.44) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11635066 | 0.77 | ALDH1A1 (0.39) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11820029 | 0.76 | KMT2A (0.37) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11634679 | 0.76 | KMT2A (0.37) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4106942-A | COMPOUNDS CONTAINING SULFIDE, KETONE, AND AMIDE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-15 | — | — | US | disclosed |