Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642724 | 0.91 | MAPT (0.56) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL11637136 | 0.90 | MAPT (0.56) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL11636658 | 0.83 | LMNA (0.61) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL21814999 | 0.81 | RAB9A (0.47) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL11637249 | 0.81 | LMNA (0.48) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL16197930 | 0.76 | MEN1 (0.47) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11336670 | 0.76 | MEN1 (0.56) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL8361904 | 0.75 | MAPT (0.58) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL11638254 | 0.75 | MAPT (0.53) | LMNAMAPTSMN1; SMN2POLBNPC1 | |
| SCHEMBL1904985 | 0.74 | NPC1 (0.57) | MAPTSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100168-A | ANALGESICS, ANTIPYRETIC, ANTIINFLAMMATORY AGENTS | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | disclosed |