Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746091 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1SRC | |
| SCHEMBL11593125 | 0.85 | PTGS2 (0.54) | PTGS2PTGS1SRC | |
| SCHEMBL10590496 | 0.83 | ESR2 (0.46) | PTGS2PTGS1SRCACHE | |
| SCHEMBL11593409 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1SRC | |
| SCHEMBL10588552 | 0.80 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1BCHECHRM1 | |
| SCHEMBL1094177 | 0.79 | PTGS2 (0.47) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL11640395 | 0.79 | PTGS2 (0.47) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL11635414 | 0.79 | PTGS2 (0.47) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL8132350 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL21157448 | 0.77 | HTR2A (0.68) | PTGS2PTGS1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124373-A | Tetrahydroindazole herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-11-07 | — | — | US | disclosed |