Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746091 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1GABRA1GABRG2GABRB3 | |
| SCHEMBL10589030 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1GABRA1GABRG2GABRB3 | |
| SCHEMBL11593125 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1GABRA1GABRG2GABRB3 | |
| SCHEMBL10590496 | 0.80 | ESR2 (0.46) | PTGS2PTGS1GABRA1ACHEKMT2A | |
| SCHEMBL11593409 | 0.80 | PTGS2 (0.48) | PTGS2PTGS1GABRA1GABRG2GABRB3 | |
| SCHEMBL11635985 | 0.80 | PTGS2 (0.49) | PTGS2PTGS1ALDH1A1ACHEBCHE | |
| SCHEMBL8582714 | 0.79 | ACHE (0.41) | PTGS2HRH2HRH3ACHEBCHE | |
| SCHEMBL3083969 | 0.77 | PTGS2 (0.48) | PTGS2PTGS1HRH2HRH3ALDH1A1 | |
| SCHEMBL11628670 | 0.77 | PTGS2 (0.50) | PTGS2PTGS1GABRA1GABRG2GABRB3 | |
| SCHEMBL28261225 | 0.74 | PTGS2 (0.45) | PTGS2PTGS1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334055-A2 | Substituted benzoxazinones, several processes and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1989-09-27 | — | — | EP | disclosed |