Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638924 | 0.94 | LIPG (0.44) | SKP2TLR8TP53CYP3A4ALOX15 | |
| SCHEMBL27498291 | 0.83 | ALDH1A1 (0.50) | SKP2TLR8SMN1; SMN2CYP3A4NR1H2 | |
| SCHEMBL27456996 | 0.82 | ALDH1A1 (0.48) | SKP2TLR8SMN1; SMN2CYP3A4NR1H2 | |
| SCHEMBL7915382 | 0.81 | TLR8 (0.38) | SKP2TLR8CYP3A4TDP1NR1H2 | |
| SCHEMBL1201130 | 0.80 | LIPG (0.45) | TLR8TP53CYP3A4ALOX15TDP1 | |
| SCHEMBL2701240 | 0.79 | LIPG (0.50) | TLR8CYP3A4NR1H2NR1H3ELANE | |
| SCHEMBL27688479 | 0.78 | LIPG (0.49) | TLR8SMN1; SMN2NR1H2NR1H3GCGR | |
| SCHEMBL4666138 | 0.78 | SKP2 (0.46) | SKP2TLR8SMN1; SMN2CYP3A4ALOX15 | |
| SCHEMBL4455067 | 0.78 | SKP2 (0.52) | SKP2TLR8SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL2831772 | 0.77 | LIPG (0.51) | TLR8SMN1; SMN2NR1H2NR1H3GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123474-A | STABILIZED THERMOPLASTIC MOLDING MATERIAL | GENERAL ELECTRIC COMPANY (US) | 1978-10-31 | — | — | US | disclosed |