Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634049 | 0.85 | NR1I2 (0.54) | MAPTNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11635060 | 0.83 | PDE3B (0.51) | MAPTLMNATP53ALDH1A1KDM4E | |
| SCHEMBL11415911 | 0.82 | LMNA (0.57) | MAPTLMNATP53ALDH1A1KDM4E | |
| SCHEMBL11157753 | 0.81 | MAPT (0.61) | MAPTLMNATP53ALDH1A1KDM4E | |
| SCHEMBL3522484 | 0.81 | MAPT (0.41) | MAPTNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL3523219 | 0.81 | MAPT (0.46) | MAPTLMNATP53ALDH1A1KDM4E | |
| SCHEMBL11637290 | 0.79 | MAPT (0.46) | MAPTLMNATP53 | |
| SCHEMBL11634768 | 0.78 | MAPT (0.53) | MAPTLMNATP53 | |
| SCHEMBL11421197 | 0.78 | NR1I2 (0.74) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11604828 | 0.77 | KMT2A (0.60) | MAPTLMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |