Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157753 | 0.85 | MAPT (0.61) | MAPTTP53LMNAKDM4EALDH1A1 | |
| SCHEMBL11636375 | 0.85 | MAPT (0.47) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11160129 | 0.85 | NR1I2 (0.50) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11415911 | 0.84 | LMNA (0.57) | MAPTTP53LMNAKDM4EALDH1A1 | |
| SCHEMBL11635741 | 0.84 | NR1I2 (0.49) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11637290 | 0.83 | MAPT (0.46) | MAPTTP53LMNA | |
| SCHEMBL11462815 | 0.83 | NR1I2 (0.48) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11634768 | 0.82 | MAPT (0.53) | MAPTTP53LMNAPGRRORA | |
| SCHEMBL11610757 | 0.82 | NR1I2 (0.58) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11604828 | 0.81 | KMT2A (0.60) | MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |