Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638254 | 0.89 | MAPT (0.53) | RAB9ANPC1LMNAMAPTPOLB | |
| SCHEMBL11638633 | 0.87 | MAOA (0.54) | RAB9ANPC1LMNAMAPTFAAH | |
| SCHEMBL11637743 | 0.85 | MAPT (0.42) | RAB9ANPC1LMNAMAPTACSL1 | |
| SCHEMBL11637249 | 0.81 | LMNA (0.48) | RAB9ANPC1LMNAMAPTTP53 | |
| SCHEMBL11639076 | 0.80 | MAOA (0.42) | RAB9ANPC1LMNAMAPTGAA | |
| SCHEMBL11637580 | 0.79 | MAOA (0.49) | LMNAMAPTTP53GAA | |
| SCHEMBL11638918 | 0.78 | MAOA (0.40) | RAB9ANPC1LMNAGAA | |
| SCHEMBL11638582 | 0.77 | MAOA (0.51) | RAB9ALMNAMAPTFAAHTP53 | |
| SCHEMBL11637702 | 0.77 | MAOA (0.66) | LMNAMAPTPOLBGAA | |
| SCHEMBL11637527 | 0.77 | MAOA (0.51) | LMNAMAPTFAAHTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100168-A | ANALGESICS, ANTIPYRETIC, ANTIINFLAMMATORY AGENTS | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | disclosed |