Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 4/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3744365 | 0.92 | CTSL (0.50) | CTSLSYKKLK7KLK5KMT2A | |
| SCHEMBL3748764 | 0.92 | CTSL (0.50) | CTSLSYKKLK7KLK5KMT2A | |
| SCHEMBL6880634 | 0.91 | CTSL (0.51) | CTSLSYKKLK7KLK5KMT2A | |
| SCHEMBL11902313 | 0.91 | CTSL (0.51) | CTSLSYKKLK7KLK5KMT2A | |
| SCHEMBL16120917 | 0.84 | CTSL (0.49) | CTSLSYKKLK7KLK5PPARA | |
| SCHEMBL1163483 | 0.83 | CYP3A4 (0.47) | CHRM1CHRM4CHRM5KMT2AHTR2C | |
| SCHEMBL21653773 | 0.83 | KMT2A (0.62) | CTSLCHRM1CHRM4CHRM5SYK | |
| SCHEMBL21653658 | 0.83 | KMT2A (0.62) | CTSLCHRM1CHRM4CHRM5SYK | |
| SCHEMBL21653776 | 0.83 | KMT2A (0.62) | CTSLCHRM1CHRM4CHRM5SYK | |
| SCHEMBL7489001 | 0.83 | KMT2A (0.62) | CTSLCHRM1CHRM4CHRM5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018796-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF ALKYL/ARALKYL (2S)-2-(TERT-BUTOXYCARBONYL)-AMINO-2-[-8-AZABICYCLO[3.2.1]OCT-3-YL]-EXO-ACETATE AND ANALOGS THEREOF: KEY INTERMEDIATES FOR THE PREPARATION OF DPPIV INHIBITORS | LUPIN LIMITED (IN) | 2011-02-17 | — | — | WO | disclosed |