Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940540 | 0.85 | PPARD (0.39) | FDPSGGPS1SMPD1 | |
| SCHEMBL961898 | 0.84 | FDPS (0.36) | FDPSGGPS1SMPD1KDM4ETP53 | |
| SCHEMBL16841368 | 0.83 | FDPS (0.35) | FDPSGGPS1SMPD1KDM4ETP53 | |
| SCHEMBL3741739 | 0.82 | FDPS (0.44) | FDPSGGPS1 | |
| SCHEMBL11515807 | 0.81 | CES2 (0.40) | FDPSGGPS1 | |
| SCHEMBL9632329 | 0.79 | FDPS (0.39) | FDPSGGPS1SMPD1KDM4ETP53 | |
| SCHEMBL10357106 | 0.78 | GGPS1 (0.42) | FDPSGGPS1SMPD1KDM4ETP53 | |
| SCHEMBL9633798 | 0.78 | GGPS1 (0.42) | FDPSGGPS1SMPD1KDM4ETP53 | |
| SCHEMBL10682984 | 0.77 | FDPS (0.47) | FDPSGGPS1SMPD1 | |
| SCHEMBL10683628 | 0.75 | GGPS1 (0.50) | FDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107191-A | PROSTAGLANDINS, BLOOD PRESSURE LOWERING, LABOR INDUCTION, REPRODUCTIVE-CYCLE REGULATION, GASTRIC ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4104474-A | PROSTAGLANDINS, HYPOTENSIVE, OXYTOCICS, ANTIFERTILITY, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4099015-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4086258-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
| US-4058564-A | PROSTAGLANDINS; HYPOTENSIVE, LABOR INDUCERS, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1977-11-15 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |