Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636109 | 0.84 | NPC1 (0.66) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11636671 | 0.81 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11639561 | 0.78 | PTPRS (0.48) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11637749 | 0.78 | KDM4E (0.65) | ALDH1A1NPC1RAB9ALMNAPTPRS | |
| SCHEMBL11634284 | 0.77 | GABRP (0.50) | ALDH1A1NPC1RAB9ALMNASIGMAR1 | |
| SCHEMBL9391119 | 0.76 | NPC1 (0.69) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11637174 | 0.75 | GABRP (0.66) | NPC1RAB9ALMNACASP3SENP7 | |
| SCHEMBL11637081 | 0.75 | CSNK2A2 (0.60) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11633630 | 0.75 | TNKS (0.57) | ALDH1A1NPC1RAB9ALMNACASP3 | |
| SCHEMBL11635892 | 0.75 | GABRP (0.68) | ALDH1A1CYP1A1CYP1A2CYP1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122200-A | 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-10-24 | — | — | US | disclosed |
| US-4097582-A | 6',2-(2'-Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-06-27 | — | — | US | disclosed |