SCHEMBL11636765

SCHEMBL11636765

NNc1cccc(OC(F)(F)C(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.48
BCR P11274 3/20 0.48
PRKCA P17252 3/20 0.48
EPHX2 P34913 1/20 0.48
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
BRAF P15056 2/20 0.41
EGFR P00533 1/20 0.41
SRC P12931 1/20 0.41
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
PRKCD Q05655 1/20 0.41
CCNB2 O95067 1/20 0.41
CCNE2 O96020 1/20 0.41
CDK1 P06493 1/20 0.41
FGFR1 P11362 1/20 0.41
CDK4 P11802 1/20 0.41
CCNB1 P14635 1/20 0.41
CCNA2 P20248 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11635732 0.98 ABL1 (0.47) ABL1BCRPRKCAEPHX2LMNA
SCHEMBL2200284 0.84 SLC22A12 (0.49) EPHX2MAPT
SCHEMBL13169816 0.83 LMNA (0.51) ABL1BCRPRKCAEPHX2LMNA
Hydrochloric Acid SCHEMBL1117983 0.82 SLC22A12 (0.48) EPHX2MAPT
SCHEMBL498326 0.81 PIM1 (0.48) ABL1BCRPRKCAEPHX2LMNA
SCHEMBL18884385 0.80 TAS2R14 (0.51) EPHX2LMNAPOLBMAPT
SCHEMBL30829042 0.80 CYP3A4 (0.48) ABL1BCRPRKCAEPHX2LMNA
SCHEMBL1560 0.80 CYP3A4 (0.48) ABL1BCRPRKCAEPHX2LMNA
SCHEMBL14418352 0.79 EPHX2 (0.48) ABL1BCRPRKCAEPHX2LMNA
SCHEMBL15754935 0.79 ABL1 (0.45) ABL1BCRPRKCAEPHX2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4077797-A COTTON PLANTS BASF AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed