SCHEMBL11637101

SCHEMBL11637101

c1ccc2c(c1)cc[n+]1c3ccccc3ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPRT1 P00492 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MITF O75030 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
CSNK2A2 P19784 2/20 0.38
CSNK2B P67870 2/20 0.38
CSNK2A1 P68400 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610868 0.70 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL669216 0.68 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL669217 0.68 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Methane SCHEMBL11666193 0.68 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL8739989 0.67 CSNK2A2 (0.50) HPRT1HTTSMN1; SMN2CSNK2A2CSNK2B
SCHEMBL9983777 0.67 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL7819998 0.67 ALDH1A1 (0.51) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL351979 0.65 TNNI3 (0.61) RAB9ACSNK2A2CSNK2BCSNK2A1ACHE
Phenanthrene SCHEMBL30932938 0.65 CYP2A6 (1.00) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL7643 0.65 CYP2A6 (1.00) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed