Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230028 | 0.80 | MEN1 (0.38) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL10950113 | 0.77 | MEN1 (0.34) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL2155982 | 0.76 | MEN1 (0.36) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL8654494 | 0.76 | KMT2A (0.45) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL7340045 | 0.76 | KMT2A (0.45) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL11000896 | 0.76 | KMT2A (0.45) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL11637347 | 0.76 | KEAP1 (0.43) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL582357 | 0.74 | KMT2A (0.44) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL7340052 | 0.73 | POLB (0.49) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL7619544 | 0.73 | KMT2A (0.43) | MEN1ESR1KMT2AESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098823-A | VASODILATION, HYPOTENSIVE AGENTS, ANTICOAGULATNS, ANTISECRETORY AGENTS, INOTROPIC AGENTS | MILES LABORATORIES, INC. (US) | 1978-07-04 | — | — | US | disclosed |