Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637093 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL29956716 | 0.76 | PTPN1 (0.56) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11614605 | 0.76 | PTPN1 (0.56) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11618420 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11485184 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL27984738 | 0.75 | ALOX15 (0.54) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11495850 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL30937511 | 0.75 | ALOX15 (0.54) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11483748 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL11881565 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127669-A | [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | disclosed |