Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637698 | 1.00 | GABRA1 (0.51) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11403862 | 0.83 | CYP3A4 (0.49) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11396633 | 0.83 | CYP3A4 (0.49) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11396636 | 0.83 | CYP3A4 (0.49) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11403851 | 0.83 | CYP3A4 (0.49) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11550413 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11550403 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11638645 | 0.81 | TRPM8 (0.44) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11638642 | 0.81 | TRPM8 (0.44) | GABRA1GABRB2GABRG2GABRB3GABRA3 | |
| SCHEMBL11636178 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125714-A | Aryl substituted cycloalkanones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125541-A | Aryl substituted ketones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |