SCHEMBL11637720

SCHEMBL11637720

CCC(C)(C)c1ccc(OCCCC(=O)Nc2ccc(OC)c(C(=O)C(Cl)C(=O)Nc3ccccc3)c2)c(C(C)(C)CC)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
MAPT P10636 5/20 0.40
MAPK1 P28482 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
NPSR1 Q6W5P4 4/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
MITF O75030 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 2/20 0.38
MDH1 P40925 1/20 0.38
MDH2 P40926 1/20 0.38
HIF1A Q16665 1/20 0.38
HDAC1 Q13547 3/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11637723 0.92 KCNK3 (0.40) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL8958674 0.88 HIF1A (0.45) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11596483 0.87 MDH1 (0.43) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11637421 0.85 MEN1 (0.41) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11594667 0.85 APOBEC3A (0.43) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL10886968 0.83 MEN1 (0.43) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL10886963 0.81 MAPT (0.42) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11326885 0.79 APOBEC3A (0.42) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11340821 0.79 SMN1; SMN2 (0.46) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL11637423 0.79 F2R (0.41) MEN1KMT2AMAPTMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4071365-A Silver halide emulsion containing two-equivalent yellow dye-forming coupler MITSUBISHI PAPER MILLS, LTD. (JA) 1978-01-31 US disclosed