SCHEMBL8958674

SCHEMBL8958674

CCC(C)(C)c1ccc(OCCCC(=O)Nc2cccc(C(=O)C(Cl)C(=O)Nc3ccccc3)c2)c(C(C)(C)CC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.45
MDH1 P40925 2/20 0.45
MDH2 P40926 2/20 0.45
ALDH1A1 P00352 3/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
HTT P42858 3/20 0.44
RAB9A P51151 2/20 0.42
GAA P10253 2/20 0.42
NPC1 O15118 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 7/20 0.42
KMT2A Q03164 7/20 0.42
MAPT P10636 4/20 0.42
MAPK1 P28482 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596483 0.96 MDH1 (0.43) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL11340821 0.91 SMN1; SMN2 (0.46) HIF1AMDH1MDH2ALDH1A1SMN1; SMN2
SCHEMBL11637720 0.88 MEN1 (0.40) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL10886968 0.87 MEN1 (0.43) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL11637723 0.86 KCNK3 (0.40) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL10906826 0.86 SMN1; SMN2 (0.57) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL11723886 0.84 HIF1A (0.45) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL11596785 0.84 HIF1A (0.45) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL8621068 0.84 HIF1A (0.52) HIF1AMDH1MDH2ALDH1A1CYP2C9
SCHEMBL10906825 0.84 HIF1A (0.52) HIF1AMDH1MDH2ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0112514-B2 Silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1996-01-17 EP disclosed
US-RE34697-E With cyan couplers, for sharp durable color images KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1994-08-16 US disclosed
EP-0159912-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-11-30 EP disclosed
US-4614710-A PHENOL DERIVED CYAN COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-09-30 US disclosed
US-4613565-A CYAN COUPLERS HAVING GOOD SOLUBILITY AND DISPERSION STABILITY; COLOR PHOTOGRAPHY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-09-23 US disclosed
US-4613564-A MIXTURE OF CYAN COUPLERS PROVIDES INCREASED STABILITY, FILMS, PAPERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-09-23 US disclosed
US-4609618-A STABLY DISPERSED CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-09-02 US disclosed
EP-0159912-A1 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1985-10-30 EP disclosed
EP-0159914-A1 Silver halide photographic material KONICA CORPORATION (JP) 1985-10-30 EP disclosed
EP-0159911-A1 Silver halide photographic material KONICA CORPORATION (JP) 1985-10-30 EP disclosed
US-4537857-A CYN, MAGENTA AND YELLOW COUPLERS; CLEAR, REPRODUCIBLE IMAGES; STABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-27 US disclosed
US-4526864-A Silver halide emulsion, cyan couplers KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-07-02 US disclosed
EP-0113124-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1984-07-11 EP disclosed
EP-0112514-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1984-07-04 EP disclosed
US-4277558-A ANTIFOGGING HYDROQUINONES OR BENZOQUINONES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-07 US disclosed
US-4228235-A HAVING STABILIZED DYE IMAGES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-10-14 US disclosed
US-4155765-A COLORFAST KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-05-22 US disclosed
US-4078936-A Silver halide emulsion containing two-equivalent yellow coupler MITSUBISHI PAPER MILLS, LTD. (JA) 1978-03-14 US disclosed
US-4071365-A Silver halide emulsion containing two-equivalent yellow dye-forming coupler MITSUBISHI PAPER MILLS, LTD. (JA) 1978-01-31 US disclosed
US-4015990-A TOCOPHEROL DERIVATIVE AS STABILIZER MITSUBISHI PAPER MILLS, LTD. (JA) 1977-04-05 US disclosed