Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624412 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1CCR2BRD4PTGS2 | |
| SCHEMBL11624546 | 0.79 | TP53 (0.44) | KDM4ENPC1RAB9AALDH1A1HCAR2 | |
| SCHEMBL9056358 | 0.70 | PTGS1 (0.36) | KDM4EALDH1A1BRD4PTGS2PTGS1 | |
| SCHEMBL31566429 | 0.69 | PTGS1 (0.38) | KDM4EALDH1A1BRD4PTGS2SMN1; SMN2 | |
| SCHEMBL22235420 | 0.69 | PTGS1 (0.38) | KDM4EALDH1A1BRD4PTGS2SMN1; SMN2 | |
| SCHEMBL20524919 | 0.69 | PTGS1 (0.52) | KDM4EALDH1A1BRD4PTGS2PTGS1 | |
| SCHEMBL8572826 | 0.65 | CYP19A1 (0.37) | ALDH1A1HCAR2HCAR3PTGS2PTGS1 | |
| SCHEMBL21845225 | 0.62 | PARP1 (0.38) | KDM4EALDH1A1PTGS2SMN1; SMN2PTGS1 | |
| SCHEMBL6971603 | 0.62 | CHRNA1 (0.40) | KDM4ENPC1RAB9AALDH1A1HCAR2 | |
| Phthalic Acid SCHEMBL27980436 | 0.62 | ALDH1A1 (0.74) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |