Methionine

Methionine

SCHEMBL1163783

CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)O.C[C@H](N)C(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.56
BHMT2 Q9H2M3 1/20 0.56
RNPEP Q9H4A4 1/20 0.50
NOS2 P35228 2/20 0.47
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
SLC7A5 Q01650 1/20 0.45
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GSR P00390 1/20 0.45
CYP1A2 P05177 1/20 0.45
GRIK1 P39086 1/20 0.45
GRM5 P41594 1/20 0.45
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL27265226 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL14485913 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL27264983 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL1163782 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL2804076 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL538646 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL15323126 0.94 BHMT (0.51) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23361954 0.94 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL8983115 0.94 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL126688 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240091313-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES Immunoforge Co., Ltd. (KR) 2024-03-21 US disclosed
EP-3311828-B1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES PHASEBIO PHARMACEUTICALS INC (US) 2021-04-07 EP disclosed
EP-3311828-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES Phasebio Pharmaceuticals, Inc. (US) 2018-04-25 EP disclosed
US-20180008677-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES PHASEBIO PHARMACEUTICALS, INC. 2018-01-11 US disclosed
US-9700598-B2 Modified vasoactive intestinal peptides PHASEBIO PHARMACEUTICALS, INC. (US) 2017-07-11 US disclosed
EP-2464370-B1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES PHASEBIO PHARMACEUTICALS INC (US) 2017-03-29 EP disclosed
US-20160220642-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES Immunoforge Co., Ltd. (KR) 2016-08-04 US disclosed
US-9029505-B2 Modified vasoactive intestinal peptides PHASEBIO PHARMACEUTICALS, INC. (US) 2015-05-12 US disclosed
EP-2464370-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES Phasebio Pharmaceuticals, Inc. (US) 2012-06-20 EP disclosed
US-20110178017-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES PHASEBIO PHARMACEUTICALS, INC. (US) 2011-07-21 US disclosed
WO-2011020091-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES PHASEBIO PHARMACEUTICALS, INC. (US) 2011-02-17 WO disclosed
EP-0472662-A4 ANTIFREEZE POLYPEPTIDES 1992-10-07 EP disclosed
US-5118792-A Fusion protein containing beta-lactamase; for increasing stroage stability of food and bioligics and to protect plants from frost DNA PLANT TECHNOLOGY CORPORATION (US) 1992-06-02 US disclosed
EP-0472662-A1 ANTIFREEZE POLYPEPTIDES DNA Plant Technology Corporation (US) 1992-03-04 EP disclosed
WO-1990013571-A1 ANTIFREEZE POLYPEPTIDES DNA PLANT TECHNOLOGY CORPORATION (US) 1990-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180008677-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES VIP, VIPR1, VIPR2 BHMT 3631/4885BHMT2 3514/4885RNPEP 783/4885
US-20110178017-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES VIP, VIPR1, VIPR2 BHMT 3631/4885BHMT2 3514/4885RNPEP 783/4885
US-20240091313-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES VIP, VIPR1, VIPR2 BHMT 3631/4885BHMT2 3514/4885RNPEP 783/4885
US-20160220642-A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES VIP, VIPR1, VIPR2 BHMT 3631/4885BHMT2 3514/4885RNPEP 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.