Methionine

Methionine

SCHEMBL538646

CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.56
BHMT2 Q9H2M3 1/20 0.56
RNPEP Q9H4A4 1/20 0.50
NOS2 P35228 2/20 0.47
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
SLC7A5 Q01650 1/20 0.45
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GSR P00390 1/20 0.45
CYP1A2 P05177 1/20 0.45
GRIK1 P39086 1/20 0.45
GRM5 P41594 1/20 0.45
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL27265226 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL14485913 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL1163783 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL27264983 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL1163782 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL2804076 1.00 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL15323126 0.94 BHMT (0.51) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23361954 0.94 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL8983115 0.94 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL126688 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117441021-A Methods and compositions for altering protein accumulation 孟山都技术有限公司 2024-01-23 CN claimed
US-20210324027-A1 MODIFIED INTERLEUKIN-7 PROTEINS AND USES THEREOF GENEXINE, INC. (KR) 2021-10-21 US claimed
CN-106834262-B A kind of linoleate isomerase mutant and its application 杭州师范大学 2019-08-16 CN claimed
CN-106834262-A A kind of linoleate isomerase mutant and its application 杭州师范大学 2017-06-13 CN claimed
US-8173871-B2 Bacterial proteins with pesticidal activity UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (MX) 2012-05-08 US claimed
EP-1642910-B1 Rationally designed antibodies ALEXION PHARMA INC (US) 2012-02-08 EP claimed
US-20110020437-A1 OLIGOPEPTIDIC COMPOUNDS AND USES THEREOF APIM THERAPEUTICS AS (NO) 2011-01-27 US claimed
US-7482435-B2 Immunoglobulin for use in human therapeutics and diagnostics ALEXION PHARMACEUTICALS, INC. (US) 2009-01-27 US claimed
EP-1589034-B1 Rationally designed antibodies ALEXION PHARMA INC (US) 2008-11-19 EP claimed
EP-1199355-B1 SULFUR ATOM-FREE ENZYME PROTEINS NAT INST OF ADVANCED IND SCIEN (JP) 2007-03-14 EP claimed
US-6100070-A HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR RECEPTOR AGONIST POLYPEPTIDE HAVING A MODIFIED AMINO ACID SEQUENCE; FOR STIMULATION OF BONE MARROW AND BLOOD CELL ACTIVATION AND GROWTH BEFORE THE EXPANDED CELLS ARE INFUSED INTO PATIENTS G. D. SEARLE & CO. (US) 2000-08-08 US claimed
US-6093395-A HUMAN INTERLEUKIN-3 VARIANT OR MUTANT PROTEINS FUNCTIONALLY CO-ADMINISTERED WITH OTHER COLONY STIMULATING FACTORS, CYTOKINES, LYMPHOKINES, INTERLEUKINS, HEMATOPOIETIC GROWTH FACTORS OR INTERLEUKIN-3 VARIANTS G. D. SEARLE & CO. (US) 2000-07-25 US claimed
US-6060047-A Co-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell production G. D. SEARLE & CO. (US) 2000-05-09 US claimed
EP-0990156-A1 CYCLIC PEPTIDE LIBRARIES AND METHODS OF USE THEREOF TO IDENTIFY BINDING MOTIFS Beth Israel Deaconess Medical Center (US) 2000-04-05 EP claimed
US-6017523-A TREATING A IMMUNODEFICIENCY, HEMATOPOIETIC OR BONE MARROW DISORDER ;STIMULANTS; ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION; MUTEINS HAVING SEVERAL VARIATIONS, PREFERABLY IN ONE TO THREE AMINO ACIDS G.D. SEARLE & CO. (US) 2000-01-25 US claimed
US-5997857-A COADMINISTERING WITH CSF, CYTOKINES, LYMPHOKINES, INTERLEUKINS, HEMATOPOIETIC GROWTH FACTORS OR IL-3 VARIANTS. G. D. SEARLE & CO. (US) 1999-12-07 US claimed
US-5997860-A Ex-vivo expansion of stem cells using combinations of interleukin-3 (IL-3) variants and other cytokines G. D. SEARLE & CO. (US) 1999-12-07 US claimed
WO-1998054577-A9 CYCLIC PEPTIDE LIBRARIES AND METHODS OF USE THEREOF TO IDENTIFY BINDING MOTIFS BETH ISRAEL HOSPITAL (US) 1999-04-01 WO claimed
US-5849875-A Human tissue factor inhibitor G. D. SEARLE & CO. (US) 1998-12-15 US claimed
WO-1998054577-A1 CYCLIC PEPTIDE LIBRARIES AND METHODS OF USE THEREOF TO IDENTIFY BINDING MOTIFS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 1998-12-03 WO claimed