Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575350 | 0.80 | CHRM2 (0.50) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL11647454 | 0.79 | SMN1; SMN2 (0.56) | OPRK1KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL11643858 | 0.76 | SIGMAR1 (0.51) | BLMPMP22KCNH2CYP3A4TSHR | |
| SCHEMBL6577621 | 0.76 | CHRM2 (0.49) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL6576125 | 0.76 | KIF11 (0.41) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL6574097 | 0.75 | CHRM2 (0.41) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL6575451 | 0.74 | CHRM2 (0.50) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL11479945 | 0.73 | KCNH2 (0.59) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL13541547 | 0.73 | KCNH2 (0.74) | SLC22A2SLC22A1PGRTHRBADRB3 | |
| SCHEMBL4937013 | 0.73 | TAAR1 (0.56) | TSHRTAAR1KIF11SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118494-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4014884-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |