Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TXN | P10599 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642718 | 0.89 | RAPGEF4 (0.42) | TSHRMAPTMEN1MAPK1KMT2A | |
| SCHEMBL1182939 | 0.78 | TSHR (0.62) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL23643491 | 0.76 | NFKB1 (0.57) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL1686537 | 0.75 | RAPGEF4 (0.56) | TSHRMAPTMEN1MAPK1KMT2A | |
| SCHEMBL8973245 | 0.74 | TSHR (0.61) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL11649921 | 0.74 | TSHR (0.40) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL10642203 | 0.72 | TSHR (0.57) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL14940191 | 0.71 | RAPGEF4 (0.54) | NFKB1CRHR1RAPGEF4 | |
| SCHEMBL11639629 | 0.71 | NFKB1 (0.47) | TSHRNFKB1MAPTMEN1MAPK1 | |
| SCHEMBL8973726 | 0.70 | NFKB1 (0.55) | TSHRNFKB1MAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104250-A | Flame-retardant polymers with 1,3,5-triazines having halo- and halo-aryl substitutents | BORG-WARNER CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4096206-A | Flame-retardant triazines | BORG-WARNER CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |