Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639400 | 0.78 | MEN1 (0.32) | HTTKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7754006 | 0.76 | HPGD (0.49) | HTTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7754004 | 0.76 | HPGD (0.49) | HTTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL11757728 | 0.76 | MAPT (0.50) | HTTKDM4EGAAL3MBTL1MEN1 | |
| SCHEMBL11757735 | 0.76 | MAPT (0.50) | HTTKDM4EGAAL3MBTL1MEN1 | |
| SCHEMBL11634628 | 0.73 | KMT2A (0.62) | HTTKDM4EGAAMEN1KMT2A | |
| SCHEMBL14863383 | 0.73 | GAA (0.37) | HTTGAAL3MBTL1MEN1KMT2A | |
| Maleic Acid SCHEMBL11635543 | 0.72 | SMN1; SMN2 (0.39) | HTTKDM4EL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6746442 | 0.71 | KDM4E (0.70) | HTTKDM4EGAAL3MBTL1MAOB | |
| SCHEMBL21519509 | 0.71 | GAA (0.47) | KDM4EGAAL3MBTL1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109008-A | SUBSTITUTED WITH AN AMIDINO AND A 1,3-DIMETHYL-2-OXO-BENZIMIDAZOL- 5-YL RADICAL | HEXACHIMIE (FR) | 1978-08-22 | — | — | US | disclosed |