Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759344 | 0.78 | MEN1 (0.41) | GAANPSR1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL11222976 | 0.76 | ALDH1A1 (0.58) | NPSR1ALDH1A1MEN1KMT2ACETP | |
| SCHEMBL24131349 | 0.75 | ALDH1A1 (0.38) | GAANPSR1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL11059185 | 0.75 | RAB9A (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10351891 | 0.73 | MEN1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL11639403 | 0.73 | HTT (0.41) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2002382 | 0.71 | GAA (0.50) | GAAHSD17B10ALDH1A1KMT2ATSHR | |
| SCHEMBL1082915 | 0.70 | MEN1 (0.69) | NPSR1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11639400 | 0.70 | MEN1 (0.32) | NPSR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL1399545 | 0.69 | SIRT1 (0.50) | GAANPSR1HSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085518-B2 | Method for the synthesis of 18F-labelled molecules | GE HEALTHCARE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| US-20140243555-A1 | METHOD FOR THE SYNTHESIS OF 18F-LABELLED MOLECULES | GE HEALTHCARE LIMITED (GB) | 2014-08-28 | — | — | US | disclosed |
| EP-2766326-A1 | METHOD FOR THE SYNTHESIS OF 18F-LABELLED BIOMOLECULES | GE Healthcare UK Limited (GB) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053941-A1 | METHOD FOR THE SYNTHESIS OF 18F-LABELLED BIOMOLECULES | GE HEALTHCARE LIMITED (GB) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243555-A1 | METHOD FOR THE SYNTHESIS OF 18F-LABELLED MOLECULES | GMPS, PAICS, DUT | GAA 30/4885NPSR1 4511/4885HSD17B10 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.