Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754006 | 1.00 | HPGD (0.49) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5332900 | 0.80 | MEN1 (0.41) | HPGDTSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL7758678 | 0.79 | PTGS2 (0.44) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7758675 | 0.79 | PTGS2 (0.44) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7756773 | 0.79 | HPGD (0.41) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7756778 | 0.79 | HPGD (0.41) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10351891 | 0.77 | MEN1 (0.48) | HPGDMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9756667 | 0.77 | L3MBTL1 (0.39) | HPGDMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5363287 | 0.77 | MEN1 (0.44) | HPGDTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL11757735 | 0.76 | MAPT (0.50) | HPGDMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702008-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2001-08-29 | — | — | EP | claimed |
| US-5856504-A | TREATING A 2-(ALKYLTHIO)BENZALDEHYDE OXIME WITH A HALOGEN COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| US-5773626-A | HALOGENATION OF A 2-(ALKYLTHIO)BENZALDEHYDE OXIME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-06-30 | — | — | US | claimed |
| EP-0805151-A1 | PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-11-05 | — | — | EP | claimed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | claimed |
| JP-8157460-A | — | — | None | — | — | JP | disclosed |
| EP-0702008-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2001-08-29 | — | — | EP | disclosed |
| EP-1081141-A1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| CN-1055466-C | Method for producing 1,2-benzisothiazol-3-ones 21678/01 | SUMITOMO SEIKA CHEMICALS (JP) | 2000-08-16 | — | — | CN | disclosed |
| US-5856504-A | TREATING A 2-(ALKYLTHIO)BENZALDEHYDE OXIME WITH A HALOGEN COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5856504-A | TREATING A 2-(ALKYLTHIO)BENZALDEHYDE OXIME WITH A HALOGEN COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5773626-A | HALOGENATION OF A 2-(ALKYLTHIO)BENZALDEHYDE OXIME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5633384-A | FROM O-ALKYLTHIOBENZONITRILES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5633384-A | FROM O-ALKYLTHIOBENZONITRILES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| JP-H08157460-A | PRODUCTION OF ISOTHIAZOLE DERIVATIVE | SUMITOMO SEIKA CHEM CO LTD | 1996-06-18 | — | — | JP | disclosed |
| US-5527917-A | Process for the preparation of 1,2-benzisothiazoles | CIBA-GEIGY CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1996017834-A1 | PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-06-13 | — | — | WO | disclosed |
| CN-1119645-A | Method for producing 1,2-benzisothiazol-3-ones 21678/01 | SUMITOMO SEIKA CHEMICALS (JP) | 1996-04-03 | — | — | CN | disclosed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |