Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394273 | 0.81 | MAOB (0.51) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL8786734 | 0.81 | MAOB (0.51) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL11405457 | 0.81 | PTGS2 (0.50) | MAOBMAOAPTPN1PTGS2SMN1; SMN2 | |
| SCHEMBL9246490 | 0.79 | MAOB (0.51) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL9618068 | 0.79 | MAOB (0.57) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL29016986 | 0.77 | MAOB (0.47) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL9618120 | 0.77 | MAOB (0.60) | MAOBMAOAPTPN1ALDH1A1SMN1; SMN2 | |
| Methylchromone SCHEMBL25934 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| Methylchromone SCHEMBL29387804 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1PTGS2ALDH1A1 | |
| SCHEMBL12622644 | 0.74 | MAOB (0.51) | MAOBMAOAPTPN1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127669-A | [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | disclosed |