Methylchromone

Methylchromone

SCHEMBL29387804

Cc1coc2ccccc2c1=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 14/20 0.56
MAOA P21397 5/20 0.56
PTPN1 P18031 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
HSD17B10 Q99714 1/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylchromone SCHEMBL25934 1.00 MAOB (0.56) MAOBMAOAPTPN1SMN1; SMN2KDM4E
Methylchromone SCHEMBL29160528 0.98 MAOB (0.55) MAOBMAOAPTPN1SMN1; SMN2KDM4E
Methylchromone SCHEMBL3456497 0.91 MAOB (0.49) MAOBMAOAPTPN1SMN1; SMN2KDM4E
SCHEMBL12183 0.82 MAOB (0.44) MAOBMAOAPTPN1SMN1; SMN2
SCHEMBL13268057 0.81 KDM4E (0.68) MAOBMAOAPTPN1SMN1; SMN2KDM4E
Benzene SCHEMBL28592905 0.80 MAOB (0.46) MAOBMAOAPTPN1SMN1; SMN2
Methylchromone SCHEMBL30169761 0.80 MAOA (0.47) MAOBMAOAPTPN1SMN1; SMN2KDM4E
SCHEMBL27755477 0.77 MAOB (0.58) MAOBMAOAPTPN1SMN1; SMN2KDM4E
Formic Acid SCHEMBL28395993 0.76 MAOB (0.49) MAOBMAOAPTPN1PTGS2
SCHEMBL5013425 0.76 ALDH1A1 (0.58) MAOBMAOAALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP disclosed
WO-2024192309-A1 CHEMICAL COMPOUNDS REACTIVE BIOSCIENCES, INC. (US) 2024-09-19 WO disclosed
CN-112041294-B Co-crystals of panthenol and compositions comprising said co-crystals 晶体工程智能研究中心 2024-02-20 CN disclosed
US-11814673-B2 Cardiovascular disease GENINCODE PLC (GB) 2023-11-14 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed