Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641654 | 0.86 | NPC1 (0.47) | LMNANPSR1KMT2ANPC1HPGD | |
| SCHEMBL11643265 | 0.84 | KDM4E (0.54) | PTGDR2MRGPRX4HPGD | |
| SCHEMBL11642707 | 0.82 | PTGDR2 (0.50) | LMNANPSR1PTGDR2ATMGAA | |
| SCHEMBL11644176 | 0.82 | TSHR (0.48) | L3MBTL1LMNANPSR1KMT2ATSHR | |
| SCHEMBL11642634 | 0.82 | MAPT (0.45) | LMNANPSR1PTGDR2RECQLPOLB | |
| SCHEMBL5990108 | 0.81 | NPC1 (0.53) | L3MBTL1LMNANPSR1KCNMA1POLB | |
| SCHEMBL11644710 | 0.79 | POLB (0.51) | PTGDR2MRGPRX4POLBGAATSHR | |
| SCHEMBL929689 | 0.77 | TSHR (0.63) | L3MBTL1PTGDR2MRGPRX4PTGER1POLB | |
| SCHEMBL611188 | 0.75 | RECQL (0.58) | L3MBTL1LMNANPSR1PPIAKCNMA1 | |
| SCHEMBL11638829 | 0.75 | POLB (0.47) | PTGDR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125538-A | ANALGESIC, ANTITUSSIVE | BRISTOL-MYERS COMPANY (US) | 1978-11-14 | — | — | US | disclosed |