Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641797 | 0.85 | HTT (0.51) | KDM4EHPGDSLC6A9MRGPRX4HTT | |
| SCHEMBL11639769 | 0.84 | L3MBTL1 (0.44) | HPGDMRGPRX4PTGDR2 | |
| SCHEMBL11641654 | 0.83 | NPC1 (0.47) | KDM4EHPGDHTT | |
| SCHEMBL11639693 | 0.81 | HPGD (0.48) | KDM4EHPGDSLC6A9PTGDR2 | |
| SCHEMBL11638450 | 0.79 | PTGDR2 (0.47) | KDM4EHPGDSLC6A9MRGPRX4HTT | |
| SCHEMBL11642634 | 0.79 | MAPT (0.45) | KDM4EHPGDHTTPTGDR2RXFP1 | |
| SCHEMBL11644181 | 0.74 | TRPV1 (0.50) | KDM4EHPGDTRPV1 | |
| SCHEMBL11507744 | 0.74 | ALDH1A1 (0.51) | KDM4EHPGDTRPV1HTT | |
| SCHEMBL6269230 | 0.72 | HTT (0.51) | KDM4EHPGDSLC6A9MRGPRX4HTT | |
| SCHEMBL8175439 | 0.71 | RORB (0.46) | KDM4EHPGDMRGPRX4RXFP1SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125538-A | ANALGESIC, ANTITUSSIVE | BRISTOL-MYERS COMPANY (US) | 1978-11-14 | — | — | US | disclosed |