Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642266 | 0.92 | PPARA (0.43) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11640419 | 0.90 | PPARG (0.49) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11566782 | 0.90 | PPARA (0.45) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11568279 | 0.88 | POLB (0.42) | CYP1A2PPARGSLC22A12ALDH1A1MAPT | |
| SCHEMBL11640145 | 0.86 | PPARG (0.43) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11597726 | 0.84 | PPARA (0.40) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11637342 | 0.83 | KMT2A (0.43) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL14497800 | 0.80 | LMNA (0.51) | PPARAALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL11564169 | 0.80 | PPARA (0.46) | CYP1A2CYP3A4ABCB11TSHRHTR2A | |
| SCHEMBL11642190 | 0.80 | BCL2L1 (0.44) | CYP1A2CYP3A4TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |