Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642266 | 0.87 | PPARA (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP2C9 | |
| SCHEMBL11640813 | 0.84 | KMT2A (0.43) | BCL2L1MCL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11640145 | 0.82 | PPARG (0.43) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11563578 | 0.80 | SLC6A3 (0.44) | BCL2L1MCL1IDO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11639892 | 0.80 | CYP1A2 (0.42) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11640419 | 0.79 | PPARG (0.49) | SMN1; SMN2CYP1A2TSHRPOLBCYP3A4 | |
| SCHEMBL11637342 | 0.78 | KMT2A (0.43) | MCL1ALDH1A1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL11564169 | 0.76 | PPARA (0.46) | ALDH1A1CYP1A2TSHRLMNACYP3A4 | |
| SCHEMBL11568596 | 0.75 | F9 (0.43) | ALDH1A1SMN1; SMN2MAPTF10LMNA | |
| SCHEMBL5206358 | 0.74 | LMNA (0.51) | ALDH1A1SMN1; SMN2MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |