SCHEMBL11640239

SCHEMBL11640239

CC(O)(CCc1ccc(Cl)cc1Cl)Cn1ccnc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.49
ADRA2C P18825 2/20 0.46
CYP2C9 P11712 4/20 0.46
CYP3A4 P08684 4/20 0.46
CYP19A1 P11511 3/20 0.46
PGR P06401 2/20 0.46
CHRM2 P08172 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
CYP2D6 P10635 2/20 0.46
CHRM1 P11229 2/20 0.46
ADRB3 P13945 2/20 0.46
IDO1 P14902 2/20 0.46
ADRA2B P18089 2/20 0.46
CHRM3 P20309 2/20 0.46
TACR2 P21452 2/20 0.46
DRD1 P21728 2/20 0.46
ACHE P22303 2/20 0.46
SLC6A2 P23975 2/20 0.46
TBXAS1 P24557 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11642697 0.93 OGG1 (0.47) OGG1ADRA2CCYP2C9CYP3A4CYP19A1
SCHEMBL11640992 0.85 CYP19A1 (0.44) OGG1CYP3A4CYP19A1CYP2D6TBXAS1
SCHEMBL11639842 0.82 CYP19A1 (0.55) OGG1CYP3A4CYP19A1TBXAS1
SCHEMBL11640908 0.81 CYP2C9 (0.50) OGG1ADRA2CCYP2C9CYP3A4CYP19A1
SCHEMBL11643156 0.81 FNTA (0.44) OGG1ADRA2CCYP2C9CYP3A4CYP19A1
SCHEMBL11640324 0.81 TP53 (0.43) OGG1ADRA2CCYP2C9CYP3A4CYP19A1
SCHEMBL11645286 0.81 CYP2C9 (0.44) OGG1ADRA2CCYP2C9CYP3A4CYP19A1
SCHEMBL11642691 0.79 CYP11B1 (0.43) CYP19A1TBXAS1ARTDP1KMT2A
SCHEMBL11643655 0.79 IDO1 (0.47) ADRA2CCYP2C9CYP3A4CYP19A1PGR
SCHEMBL11644197 0.79 CYP2C9 (0.47) OGG1ADRA2CCYP2C9CYP3A4CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4123542-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS SYNTEX (U.S.A.) INC. (US) 1978-10-31 US disclosed