Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644511 | 0.86 | AR (0.43) | CYP19A1CYP11B1CYP11B2ARALDH1A1 | |
| SCHEMBL11640239 | 0.85 | OGG1 (0.49) | CYP19A1ARMAPK1CYP1A2CYP3A4 | |
| SCHEMBL11280202 | 0.81 | CYP11B1 (0.47) | CYP19A1CYP11B1CYP11B2ALOX15POLB | |
| SCHEMBL11643282 | 0.81 | CYP11B1 (0.51) | CYP19A1CYP11B1CYP11B2ALOX15POLB | |
| SCHEMBL11639842 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2ALDH1A1CYP3A4 | |
| SCHEMBL11642697 | 0.78 | OGG1 (0.47) | CYP19A1ARMAPK1CYP1A2CYP3A4 | |
| SCHEMBL11641142 | 0.78 | TP53 (0.43) | CYP19A1CYP11B1CYP11B2ALDH1A1ALOX15 | |
| SCHEMBL11607374 | 0.76 | ALDH1A1 (0.57) | CYP19A1CYP11B1CYP11B2ALDH1A1ALOX15 | |
| SCHEMBL11642691 | 0.76 | CYP11B1 (0.43) | CYP19A1CYP11B1CYP11B2ARPOLB | |
| SCHEMBL11271904 | 0.76 | CYP11B1 (0.46) | CYP19A1CYP11B1CYP11B2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123542-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |