Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 8/20 | 0.44 |
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | CA9 | Q16790 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642150 | 0.88 | MAPT (0.50) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL11639673 | 0.80 | CA12 (0.49) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL11643613 | 0.77 | CA1 (0.62) | MAPTPKMPOLBSMN1; SMN2TDP1 | |
| SCHEMBL10428509 | 0.75 | L3MBTL1 (0.52) | MAPTPKMPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL1700918 | 0.74 | BRD4 (0.43) | — | |
| SCHEMBL11227665 | 0.73 | MAPT (0.50) | MAPTPKMPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25222247 | 0.73 | BRD4 (0.43) | — | |
| SCHEMBL1700338 | 0.72 | BRD4 (0.44) | — | |
| SCHEMBL1700564 | 0.72 | BRD4 (0.44) | — | |
| SCHEMBL1700341 | 0.72 | BRD4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | claimed |
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | disclosed |