Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642150 | 0.85 | MAPT (0.50) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL11640285 | 0.80 | MAPT (0.64) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL11643842 | 0.78 | CA2 (0.54) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL1700421 | 0.76 | VCAM1 (0.58) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL11643613 | 0.76 | CA1 (0.62) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL11642131 | 0.76 | CA2 (0.49) | CA12CA1CA2CA9VCAM1 | |
| SCHEMBL6634074 | 0.76 | ALDH1A1 (0.57) | POLBGALR2LMNAMAPTTDP1 | |
| SCHEMBL2267794 | 0.76 | POLB (0.51) | POLBGALR2LMNAMAPTTDP1 | |
| SCHEMBL30807120 | 0.76 | ALDH1A1 (0.57) | POLBGALR2LMNAMAPTTDP1 | |
| SCHEMBL6832051 | 0.74 | POLB (0.50) | VCAM1POLBGALR2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | claimed |
| US-4094982-A | PYRIDINE SULFONAMIDES AND THEIR USE AS ANTICOCCIDIAL AGENTS | SANKYO COMPANY LIMITED (JA) | 1978-06-13 | — | — | US | disclosed |