SCHEMBL11640367

SCHEMBL11640367

CCC(=O)Nc1cc(NC(=O)CC)cc([N+](=O)[O-])c1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
ACP1 P24666 1/20 0.52
KMT2A Q03164 6/20 0.50
POLB P06746 4/20 0.50
MEN1 O00255 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MITF O75030 1/20 0.50
XBP1 P17861 1/20 0.50
HTT P42858 1/20 0.50
GAA P10253 1/20 0.49
NR4A1 P22736 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356341 0.90 TSHR (0.52) CYP1A2CYP3A4CYP2C9ACP1KMT2A
SCHEMBL10657866 0.84 ACP1 (0.54) ACP1KMT2APOLBMEN1ALDH1A1
SCHEMBL5213509 0.83 CYP1A2 (0.78) CYP1A2CYP3A4CYP2C9KMT2APOLB
SCHEMBL30957465 0.83 CYP1A2 (0.78) CYP1A2CYP3A4CYP2C9KMT2APOLB
SCHEMBL3090260 0.82 POLB (0.67) CYP1A2CYP3A4CYP2C9KMT2APOLB
Hydrochloric Acid SCHEMBL27290577 0.82 CYP1A2 (0.76) CYP1A2CYP3A4CYP2C9KMT2APOLB
SCHEMBL1706183 0.82 KMT2A (0.65) KMT2APOLBMEN1ALDH1A1MAPT
SCHEMBL10876285 0.81 MEN1 (0.58) ACP1KMT2APOLBMEN1ALDH1A1
SCHEMBL27647737 0.80 MEN1 (0.60) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL7833515 0.79 SMN1; SMN2 (0.69) CYP1A2CYP3A4KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4127646-A ANTIALLERGENS SMITHKLINE CORPORATION (US) 1978-11-28 US disclosed