Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640367 | 0.90 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL15156475 | 0.83 | TSHR (0.59) | TSHRKMT2AMEN1LMNAMAPT | |
| SCHEMBL15156473 | 0.83 | TSHR (0.59) | TSHRKMT2AMEN1LMNAMAPT | |
| SCHEMBL9352334 | 0.82 | SMN1; SMN2 (0.61) | TSHRCYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL11858419 | 0.82 | ALDH1A1 (0.53) | TSHRCYP1A2CYP2C9KMT2AMEN1 | |
| SCHEMBL12240557 | 0.81 | CYP3A4 (0.59) | TSHRCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL5213509 | 0.78 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL30957465 | 0.78 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27290577 | 0.77 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9KMT2AMEN1 | |
| SCHEMBL1706183 | 0.77 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425345-B1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| US-5254135-A | Applying indole dye, developing with oxidizing system | L'OREAL (FR) | 1993-10-19 | — | — | US | disclosed |
| CN-1051669-A | With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0425345-A1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | L'OREAL (FR) | 1991-05-02 | — | — | EP | disclosed |