Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20382857 | 0.89 | KMT2A (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL6934507 | 0.89 | KMT2A (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL11640499 | 0.89 | KMT2A (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL12240557 | 0.86 | CYP3A4 (0.59) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL10970617 | 0.86 | RAB9A (0.85) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL22270636 | 0.85 | KMT2A (0.65) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL13139888 | 0.85 | HPGD (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL13019006 | 0.84 | KMT2A (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL17933421 | 0.84 | POLB (0.56) | POLBKMT2ARAB9ANR4A1ALDH1A1 | |
| SCHEMBL14670859 | 0.84 | L3MBTL1 (0.61) | POLBKMT2ARAB9ANR4A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021220011-A1 | ANTI-INFECTIVE BICYCLIC PEPTIDE CONJUGATES | BICYCLETX LIMITED (GB) | 2021-11-04 | — | — | WO | disclosed |
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| WO-2018127699-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-12 | — | — | WO | disclosed |
| US-10010626-B2 | Molecular constructs with targeting and effector moieties | Immunwork Inc. (TW) | 2018-07-03 | — | — | US | disclosed |
| US-20160208021-A1 | Molecular constructs with targeting and effector moieties | Immunwork Inc. (TW) | 2016-07-21 | — | — | US | disclosed |
| US-20160206754-A1 | Molecular constructs for treating tumors | Immunwork Inc. (TW) | 2016-07-21 | — | — | US | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206754-A1 | Molecular constructs for treating tumors | SNRPE, TP53, DCLRE1B | POLB 1489/4885KMT2A 2366/4885RAB9A 2111/4885 |
| US-10010626-B2 | Molecular constructs with targeting and effector moieties | CD2BP2, HAVCR2, DCLRE1B | POLB 2337/4885KMT2A 3371/4885RAB9A 1062/4885 |
| US-20160208021-A1 | Molecular constructs with targeting and effector moieties | CD2BP2, HAVCR2, DCLRE1B | POLB 2337/4885KMT2A 3371/4885RAB9A 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.