Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | NGFR | P08138 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643685 | 0.84 | GPR35 (0.65) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11641176 | 0.82 | GPR35 (0.73) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11811478 | 0.81 | GPR35 (0.54) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11640418 | 0.75 | NGFR (0.54) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11640408 | 0.75 | GPR35 (0.50) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11640415 | 0.75 | GPR35 (0.50) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9321122 | 0.73 | GPR35 (0.59) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9452339 | 0.69 | NGFR (0.67) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9452295 | 0.69 | KDM4E (0.67) | GPR35KDM4EMEN1HPGDKMT2A | |
| SCHEMBL11698420 | 0.68 | NGFR (0.71) | GPR35KDM4EMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |