Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810085 | 0.84 | GPR35 (0.70) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL11641176 | 0.83 | GPR35 (0.73) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL11640411 | 0.81 | GPR35 (0.49) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL11814201 | 0.76 | GPR35 (0.59) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL11814202 | 0.75 | GPR35 (0.57) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL9069080 | 0.70 | GPR35 (1.00) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL11807432 | 0.69 | GLA (0.68) | GPR35KDM4ETDP1HPGDGLA | |
| SCHEMBL11811454 | 0.68 | GPR35 (0.49) | GPR35KDM4ETDP1MEN1HPGD | |
| Xanthurenate SCHEMBL4455363 | 0.68 | KDM4E (1.00) | GPR35KDM4ETDP1MEN1HPGD | |
| SCHEMBL1759095 | 0.67 | KDM4E (0.69) | GPR35KDM4ETDP1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953598-A | ASTHMA OR RHINITIS TREATMENT | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | claimed |