Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 7/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784984 | 0.79 | PPARG (0.52) | PPARGPPARAL3MBTL1ATMPOLB | |
| SCHEMBL3391787 | 0.78 | PPARG (0.50) | PPARGPPARAL3MBTL1ATMPOLB | |
| SCHEMBL11637402 | 0.77 | PPARA (0.54) | PPARGPPARAATMSMN1; SMN2CA12 | |
| SCHEMBL22634087 | 0.72 | IDO1 (0.53) | L3MBTL1IDO1NOS3NOS1NOS2 | |
| SCHEMBL11572417 | 0.72 | MME (0.59) | IDO1NPSR1 | |
| SCHEMBL6954426 | 0.71 | PPARG (0.49) | PPARGPPARAL3MBTL1ATMIDO1 | |
| SCHEMBL11572384 | 0.71 | TDP1 (0.54) | PPARAL3MBTL1TDP1NPSR1CA2 | |
| SCHEMBL11574064 | 0.71 | ALDH1A1 (0.62) | POLBNPSR1CA2 | |
| SCHEMBL14602855 | 0.70 | ALDH1A1 (0.57) | IDO1NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL28910989 | 0.70 | L3MBTL1 (0.48) | PPARGPPARAL3MBTL1ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108854-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
| US-3997584-A | Substituted glycines and intermediates thereof | SMITHKLINE CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3994954-A | Process for preparing substituted glycines | SMITHKLINE CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |