Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640659 | 0.91 | KMT2A (0.63) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| Dimetacrine SCHEMBL29578094 | 0.88 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| Dimetacrine SCHEMBL50120 | 0.88 | CYP2D6 (1.00) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| SCHEMBL11639312 | 0.83 | KMT2A (0.57) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| SCHEMBL507636 | 0.82 | KMT2A (0.51) | CYP2D6CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL319784 | 0.82 | KMT2A (0.51) | CYP2D6CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL11640444 | 0.81 | CYP2D6 (0.58) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| SCHEMBL11639729 | 0.80 | CYP2D6 (0.57) | CYP2D6CYP1A2KMT2ALMNAHRH1 | |
| SCHEMBL23865489 | 0.80 | TP53 (0.50) | CYP2D6CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL507840 | 0.79 | CYP1A2 (0.49) | CYP2D6CYP1A2KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | disclosed |
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |