Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CBX7 | O95931 | 2/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.48 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202873 | 0.86 | GPR55 (0.56) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28501538 | 0.85 | KMT2A (0.62) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31559833 | 0.85 | TP53 (0.52) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7014237 | 0.85 | TP53 (0.52) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5555176 | 0.83 | TP53 (0.45) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7376832 | 0.82 | PARK7 (0.52) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL319784 | 0.82 | KMT2A (0.51) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL507636 | 0.82 | KMT2A (0.51) | TP53ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11640659 | 0.82 | KMT2A (0.63) | TP53KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL5544420 | 0.82 | TP53 (0.44) | TP53ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |