Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640552 | 0.91 | CYP2D6 (0.78) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL23865489 | 0.82 | TP53 (0.50) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL31559833 | 0.81 | TP53 (0.52) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL7014237 | 0.81 | TP53 (0.52) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL9202873 | 0.78 | GPR55 (0.56) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL507636 | 0.78 | KMT2A (0.51) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL319784 | 0.78 | KMT2A (0.51) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL7376832 | 0.78 | PARK7 (0.52) | KMT2ACYP2D6LMNAMAPTSLC6A4 | |
| Dimetacrine SCHEMBL50120 | 0.78 | CYP2D6 (1.00) | KMT2ACYP2D6CYP1A2LMNAMAPT | |
| Dimetacrine SCHEMBL29578094 | 0.78 | CYP2D6 (1.00) | KMT2ACYP2D6CYP1A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123543-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-10-31 | — | — | US | disclosed |
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |