Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812782 | 0.80 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL1507939 | 0.77 | DPP7 (0.39) | ALDH1A1MMP1MMP3MAPTLMNA | |
| SCHEMBL10505058 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| SCHEMBL7369696 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| SCHEMBL2715770 | 0.74 | AAK1 (0.42) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| SCHEMBL2129974 | 0.74 | AAK1 (0.42) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| SCHEMBL7772667 | 0.74 | RAB9A (0.38) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| Water SCHEMBL29947214 | 0.72 | AAK1 (0.41) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| Water SCHEMBL29902298 | 0.72 | AAK1 (0.41) | KDM4EALDH1A1MMP1MMP3MMP8 | |
| SCHEMBL11681136 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101031559-A | Amino cyclic urea derivative, preparation method thereof and medical application of amino cyclic urea derivative as kinase inhibitor | AVENTIS PHARMA SA (FR) | 2007-09-05 | — | — | CN | disclosed |
| US-4096259-A | PSCHOLOGICAL DISORDERS | BUZAS ANDRE | 1978-06-20 | — | — | US | disclosed |