Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11085674 | 0.81 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3L3MBTL1CYP11B1 | |
| Fumaric Acid SCHEMBL11085704 | 0.81 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3L3MBTL1CYP11B1 | |
| Benzene SCHEMBL11636032 | 0.81 | L3MBTL1 (0.45) | L3MBTL1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL11640422 | 0.80 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3L3MBTL1KMT2A | |
| SCHEMBL2705061 | 0.80 | RECQL (0.60) | SLC6A4SLC6A2SLC6A3RECQLALDH1A1 | |
| Ethylene SCHEMBL11641519 | 0.80 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1TDP1KCNMA1 | |
| Hydrochloric Acid SCHEMBL11638333 | 0.79 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3L3MBTL1KMT2A | |
| SCHEMBL11636028 | 0.76 | L3MBTL1 (0.42) | L3MBTL1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL611188 | 0.76 | RECQL (0.58) | L3MBTL1KMT2AMEN1TDP1KCNMA1 | |
| SCHEMBL10958118 | 0.75 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1TDP1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099012-A | ANTIANXIETY, ANTIDEPRESSANT | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4028381-A | ANTIANXIETY AND ANTIDEPRESSANT AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-4022800-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4022801-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-3947585-A | ANTIANXIETY, ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3939271-A | Antidepressive and antianxiety composition comprising 2-pyrazolyl-benzophenones | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |