Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11638333 | 0.99 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3OPRK1P2RX7 | |
| SCHEMBL11637420 | 0.89 | P2RX7 (0.39) | OPRK1P2RX7ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11636354 | 0.89 | P2RX7 (0.39) | OPRK1P2RX7ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11637516 | 0.88 | P2RX7 (0.38) | OPRK1P2RX7ALDH1A1MAPTL3MBTL1 | |
| Ethylene SCHEMBL11638672 | 0.86 | P2RX7 (0.37) | OPRK1P2RX7ALDH1A1MAPTL3MBTL1 | |
| Phosphoric Acid SCHEMBL11637858 | 0.84 | SCN9A (0.37) | OPRK1P2RX7ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11639647 | 0.83 | GRM5 (0.43) | ALDH1A1MAPTHPGD | |
| SCHEMBL11639547 | 0.81 | OPRK1 (0.34) | OPRK1P2RX7ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11640644 | 0.80 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11636391 | 0.79 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099012-A | ANTIANXIETY, ANTIDEPRESSANT | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4022800-A | ANTIANXIETY AND ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-3939271-A | Antidepressive and antianxiety composition comprising 2-pyrazolyl-benzophenones | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |