Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 15/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 11/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454176 | 0.80 | MAPK8 (0.45) | MAPK8MAPK9PRKD3CTSKMAPK10 | |
| SCHEMBL11447309 | 0.79 | MAPK8 (0.62) | MAPK8MAPK9PRKD3MAPK10KDM4E | |
| SCHEMBL11642103 | 0.76 | MAPK8 (0.41) | MAPK8MAPK9PRKD3MAPK10 | |
| SCHEMBL8888556 | 0.73 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KDM4EALDH1A1 | |
| SCHEMBL11702984 | 0.73 | MAPK8 (0.43) | MAPK8MAPK9PRKD3MAPK10KDM4E | |
| SCHEMBL11701910 | 0.73 | ADORA1 (0.52) | MAPK8MAPK9MAPK10LMNAHTT | |
| SCHEMBL8889038 | 0.72 | MAPK8 (0.48) | MAPK8MAPK9MAPK10LMNAKDM4E | |
| SCHEMBL8963971 | 0.71 | MAPK8 (0.44) | MAPK8MAPK9PRKD3LMNAMAPT | |
| SCHEMBL8889019 | 0.71 | MAPK8 (0.47) | MAPK8MAPK9MAPK10LMNAKDM4E | |
| SCHEMBL11704744 | 0.69 | MAPK8 (0.54) | MAPK8MAPK9MAPK10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066637-A | BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |