Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447309 | 0.81 | MAPK8 (0.62) | MAPK8HPGDALDH1A1KDM4EMAPK9 | |
| SCHEMBL11701910 | 0.77 | ADORA1 (0.52) | MAPK8HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8888556 | 0.75 | MAPK8 (0.49) | MAPK8HPGDALDH1A1KDM4EMAPK9 | |
| SCHEMBL11702984 | 0.74 | MAPK8 (0.43) | MAPK8HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL11704744 | 0.74 | MAPK8 (0.54) | MAPK8HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8889038 | 0.74 | MAPK8 (0.48) | MAPK8HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL11454176 | 0.73 | MAPK8 (0.45) | MAPK8HPGDALDH1A1KDM4EMAPK9 | |
| SCHEMBL8889019 | 0.72 | MAPK8 (0.47) | MAPK8HPGDALDH1A1KDM4EKMT2A | |
| SCHEMBL11642106 | 0.71 | MAPK8 (0.43) | MAPK8HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL11581534 | 0.71 | ALDH1A1 (0.42) | HPGDALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463995-B1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| EP-0463995-A1 | Azo dyestuffs with 2-alkylamino-3-cyano-4,6-diaminopyridines as coupling components | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |